Found this article, which I found interesting because because of my problem with sarcasm:
THE ANATOMY OF SARCASM: RESEARCHERS REVEAL HOW THE BRAIN HANDLES THIS COMPLEX COMMUNICATION .
Sadly, the article only describes the mechanisms involved in understanding sarcasm (I guess I must have quite a few friends with brain lesions) but not the mechanisms for making sarcastic statements. Of course, it’s likely to be the same parts of the brain that govern the behaviour.
So there’s hope for those with especially sarcastic partners. A simple lobotomy can make life much more enjoyable!